艾滋病毒感染者与对照者之间的睡眠相关呼吸障碍指数的变化:一个匹配的病例对照研究
Yen-Chin Chen1,2,3,4, Chang-Chun Chen5, Wen-Kuei Lin6
1College of Medicine, National Sun Yat-sen University, Tainan, Taiwan. yenchin2427@gmail.com.
BMC infectious diseases
|April 30, 2024
概括
艾滋病毒感染者 (PLWH) 和患有类似睡眠相关呼吸障碍 (SRBD) 的对照者表现出不同的睡眠模式. PLWH经历了更多的中央呼吸暂停,改变了睡眠阶段,增加了与嗜睡有关的问题.
科学领域:
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 与睡眠相关的呼吸障碍 (SRBD) 和艾滋病毒感染会破坏睡眠架构并引起痛苦.
- 了解艾滋病毒感染者 (PLWH) 和具有类似SRBD严重程度的对照者之间的阻塞模式,睡眠架构和痛苦之间的差异至关重要.
研究的目的:
- 为了比较阻塞性模式,睡眠架构和PLWH和HIV-seronegative对照之间的身体/心理痛苦,对SRBD严重程度进行了匹配.
主要方法:
- 采用了一种匹配的病例控制研究设计.
- 感染艾滋病毒的男性 (病例) 与感染艾滋病毒的血清阴性男性 (对照组) 进行了比较,并根据SRBD严重程度进行了匹配.
- 数据是在2016年至2019年期间收集的.
主要成果:
- 这项研究包括108名男性 (54例,54例对照),平均年龄为33.75岁.
- PLWH的中央呼吸暂停指数 (CI) 较高,睡眠架构发生了变化,包括更少的第三阶段睡眠和更快速的眼动 (REM) 睡眠.
- 导致交通事故的夜间尿尿和嗜睡在PLWH中更为频繁.
结论:
- 在PLWH中早期检测和治疗SRBD可以减轻风险.
- 解决PLWH中SRBD的根本原因可能会减少与睡眠有关的交通事故.
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