在患有急性髓性白血病的儿童体质指数,身高和体重的纵向变化
Xiaojia Wen1, Hongbo He1, Ruidong Zhang1
1Leukemia Department, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Clinical Discipline of Pediatric Hematology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children's Hospital, Capital Medical University, National Center for Children's, 56 Nanlishi Road, Beijing, 100045, China.
BMC pediatrics
|April 30, 2024
概括
儿科急性髓性白血病 (AML) 治疗影响儿童的生长,观察到体重和体重指数 (BMI) 的显著变化. 监测这些增长指标对于更好的AML患者结果至关重要.
科学领域:
- 儿科瘤学 儿科瘤学
- 增长和发展 增长和发展
- 血液学恶性瘤是什么
背景情况:
- 急性髓性白血病 (AML) 显著影响儿科患者的生长.
- 在AML治疗期间和之后的长度生长变化需要彻底调查.
研究的目的:
- 分析中国儿科AML患者的身高预测和纵向生长变化.
- 将生长变化与治疗结果联系起来.
- 评估AML治疗期间的身体质量指数 (BMI) 动态.
主要方法:
- 研究了88名患有AML的儿童,跟踪了BMI,身高和体重与生长百分位曲线.
- 从诊断到治疗后2年的评估变化.
- 基于不同BMI水平的AML结果进行比较.
主要成果:
- 体重不足的患病率从诊断到整合治疗时增加.
- 在整合期间,低BMI是最高的 (23.08%);治疗后超重的流行率达到20%.
- 诊断时和化疗期间不健康的BMI与较差的AML结果相关.
- 所有患者的最终身高都在基因预测范围之内.
结论:
- 医生必须密切监测儿童AML患者的身高和体重变化.
- 在关键治疗阶段,对生长异常的及时干预至关重要.
- 增长监测是改善儿科AML患者护理的关键.
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