手术前的TSH水平对经过垂体外科手术的患者外科并发症的影响
Gizem Kirbas1, Murat Yasar Ozkalkanli2, Ahmet Salih Tuzen2
1Anesthesiology and Reanimation Department, Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey. gizembas35@gmail.com.
European journal of medical research
|April 30, 2024
概括
甲状腺刺激激素 (TSH) 水平升高与经过垂体外科手术的患者的术后死亡风险增加有关. 仔细监测TSH对于管理手术风险至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 神经外科 神经外科
- 麻醉学 麻醉学
背景情况:
- 下垂体外科手术由于腺体位置和荷尔蒙影响而带来了独特的麻醉挑战.
- 甲状腺刺激激素 (TSH) 在荷尔蒙平衡中起着至关重要的作用,可能会影响手术结果.
研究的目的:
- 为了回顾分析手术前的TSH水平和经过垂体外科手术的患者的术后并发症之间的关联.
- 为了确定TSH水平是否预测下垂体瘤切除后的不良事件或死亡率.
主要方法:
- 追溯分析了在2017年至2022年期间接受了下垂体手术的135名患者.
- 根据手术前的TSH水平 (低,正常,高) 患者被分为三组.
- 在TSH组中比较术后并发症率和28天死亡率.
主要成果:
- 在TSH组之间没有观察到常见的术后并发症 (例如,表,恶心,高血压) 的显著差异.
- 两组之间在手术后的无味糖尿病发病率上发现了显著的差异.
- 在高TSH组 (25%的发病率) 发现28天死亡率的统计显著增加.
结论:
- 术前的TSH水平高于正常范围与垂体外科手术患者的术后死亡风险较高有关.
- 测定TSH水平可能是一个有价值的工具,用于在下垂体手术患者的风险分层.
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