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Updated: Jun 27, 2025

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创伤后急性疼痛胺:一个务实的,随机的临床试验

James M Klugh1, Thaddeus J Puzio, Michael W Wandling

  • 1From the Department of Surgery (J.M.K., T.J.P., M.W.W., C.J.G.-F., L.S.K., J.A.H.), Center for Translational Injury Research, Department of Surgery (C.G., C.E.W.), McGovern Medical School at UTHealth; Department of Emergency Medicine (P.B.S., S.J.P.), The University of Texas Medical Center at Houston, Houston, Texas; Department of Anesthesia (J.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas; Department of Anesthesiology (C.T.S.), McGovern Medical School at UTHealth, Houston, Texas.

The journal of trauma and acute care surgery
|May 1, 2024
PubMed
概括

将分离式胺注入剂 (KI) 添加到多式疼痛疗法中,显著减少了创伤患者的住院阿片类药物暴露. 这种方法提供了一种安全的补充,用于减少监控环境中的阿片类药物使用.

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Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
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Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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