维生素D与青少年副甲状腺激素和骨矿物质密度之间的关系
Ainur Donayeva1, Ainur Amanzholkyzy1, Ibrahim A Abdelazim2
1Department of Normal Physiology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Przeglad menopauzalny = Menopause review
|May 1, 2024
概括
青少年女孩的维生素D水平较低与较高的副甲状腺激素和较低的骨矿物质密度有关. 这项研究强调了维持足够的25-基维生素D对于青少年骨健康的重要性.
科学领域:
- 内分泌学 在内分泌学.
- 儿童骨健康 儿童骨健康
- 营养科学 营养科学
背景情况:
- 维生素D缺乏是青少年群体日益关注的问题.
- 甲状腺激素 (PTH) 和骨矿物质密度 (BMD) 是骨健康的关键指标.
- 了解25-基维生素D (25(OH) D),PTH和BMD之间的相互作用对于青少年的发育至关重要.
研究的目的:
- 为了研究25-基维生素D (25(OH) D) 水平和副甲状腺激素 (PTH) 在青少年女孩之间的关系.
- 在这个人口群体中,确定25...OH) D和骨矿物质密度 (BMD) 之间的关联.
- 探索与维生素D状态有关的PTH和BMD之间的相关性.
主要方法:
- 一项涉及200名青少年女孩的横截面研究.
- 测量了血清中25...OH) D,PTH和其他相关激素的水平.
- 评估了骨矿物质密度 (BMD) 和T-分数;参与者按25...OH) D水平进行分类.
主要成果:
- 与对照组相比,患有25...OH) D缺乏症的青少年表现出明显更高的PTH水平 (p=0.02).
- 25.. 缺乏OH) D的女孩在统计学上表现出比正常对照群体更低的BMD (p=0.01).
- 在25(OH) D和PTH (r=-0.9175) 之间以及PTH和BMD (r=-0.7006) 之间发现了显著的负相关性. 在25(OH) D和BMD之间观察到正相关性 (r=0.756).
结论:
- 青少年甲状腺激素水平升高与25-基维生素D的降低和骨矿物质密度的降低显著相关.
- 适当的25-基维生素D水平与青少年女孩的骨矿物质密度正相关.
- 这些发现强调了维生素D在维持青少年骨健康和荷尔蒙平衡方面的关键作用.
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