比较两种认知查工具在老年人中识别灰色和白色物质脑损伤的有效性
Paula Andreatta Maduro1,2,3, Manoel Pereira Guimarães2, Mateus de Sousa Rodrigues2,3
1Post-Graduation Program in Health Sciences (PPGCS), University of Pernambuco (UPE), Recife, PE 50100-130, Brazil.
Journal of aging research
|May 1, 2024
概括
迷你心理状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA) 有效地检测老年人的大脑损伤. MMSE识别了中间叶缩,而MoCA检测了白质病变,建议综合使用以进行综合评估.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 放射学 放射学是一门学科.
背景情况:
- 衰老与大脑结构变化和认知能力下降有关.
- 检测老年人脑损伤的非侵入性方法对于及时干预至关重要.
研究的目的:
- 为了比较小型精神状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA) 在识别灰色和白质脑损伤方面的准确性.
- 评估这些工具在老年人中具有不同程度的认知障碍.
主要方法:
- 90名老年人 (平均年龄69岁) 被分为没有认知障碍,轻度或中度认知障碍.
- 磁共振成像 (MRI) 分析了大脑损伤; 应用了Fazekas和Scheltens尺度.
- 推理统计比较了认知群体之间的变量.
主要成果:
- 在56.7%的参与者中存在认知障碍.
- 认知障碍与中叶缩相关 (p=0.001).
- MMSE发现了MTL缩 (p<0.05);MoCA发现了周周结膜白质 (PWM) 异常 (p<0.05).
结论:
- 在老年人中,MMSE和MoCA有效地识别了灰色和白质脑损伤.
- MMSE得分与MTL缩相关,而MoCA得分与PWM病变相关.
- 建议同时使用MMSE和MoCA来评估不同大脑区域的结构变化.
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