在低风险的年轻人群中进行过导管大动脉置换:双刃剑?
Sukhdeep Bhogal1, Akash Batta2
1Department of Cardiology, Sovah Health, Martinsville, VA 24112, United States.
World journal of cardiology
|May 1, 2024
概括
过导管大动脉置换 (TAVR) 是严重大动脉狭窄的标准,但它在年轻患者的使用需要仔细考虑长期结果和个人因素.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 透管大动脉置换 (TAVR) 现在是症状严重的大动脉狭窄症的标准干预方法,特别是在中等至高风险患者中.
- 美国食品和药物管理局对低风险患者的TAVR的批准是在随机试验之后进行的,尽管这些试验排除了具有特定解剖挑战的个体.
- 目前还没有针对TAVR的随机试验,专门针对年轻患者群体.
更多相关视频
05:31Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
2.8K
12:17Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
11.3K
相关概念视频
01:16Heart Valves
4.6K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
4.6K
01:23Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
169
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
169