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Updated: Jun 27, 2025

Natural Killer NK and CAR-NK Cell Expansion Method using Membrane Bound-IL-21-Modified B Cell Line
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自给自足的初级自然杀手细胞被设计成表达T细胞受体和介质白素-15表现出改善的效应器功能和持久性

Els P van Hees1, Laura T Morton1, Dennis F G Remst1

  • 1Department of Hematology, Leiden University Medical Centre (LUMC), Leiden, Netherlands.

Frontiers in immunology
|May 1, 2024
PubMed
概括

经过基因工程改造的自然杀手 (NK) 细胞表达T细胞受体 (TCR) 并分泌IL-15,表现出增强的抗瘤活性. 这种新的NK:TCR/IL-15疗法对治疗异质瘤有前途,但由于潜在的副作用,需要仔细监测.

关键词:
在Bob1中,Bob1是指Bob1.在 NK 细胞中,NK 细胞是 NK 细胞.这种T细胞受体是T细胞受体.癌症 癌症 癌症 癌症 癌症免疫疗法 免疫疗法介质蛋白-15 介质蛋白-15多发性骨髓瘤是多发性骨髓瘤的一种.

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