肺体积减小手术是安全的,并导致患者的功能改善,这些患者未能或不能接受支气管镜肺体积减小手术
Jessica Magarinos1, Aron Egelko1, Gerard J Criner2
1Department of General Surgery, Temple University Hospital, Philadelphia, Pa.
JTCVS open
|May 1, 2024
概括
肺体积减小手术 (LVRS) 对不适用于支气管镜肺体积减小手术 (BLVR) 的晚期肺气患者提供了显著的功能改善. 这项研究证实了LVRS在这个特定的患者群体中的安全性和有效性.
科学领域:
- 肺部医学 肺部医学
- 胸部外科手术 胸部外科手术
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 支气管镜式肺体积减小 (BLVR) 是晚期肺气的主要治疗方法.
- 并非所有肺气患者都是BLVR的候选人或受益者.
- 肺体积减小手术 (LVRS) 仍然是部分患者的选择.
研究的目的:
- 评估在BLVR失败或不符合条件的患者中LVRS的结果.
- 评估LVRS在具有挑战性的肺气患者队列中的安全性和有效性.
主要方法:
- 对67名接受LVRS治疗的患者进行回顾性分析,以治疗上叶主导的肺气.
- 在2018年3月至2022年12月期间进行胸腔镜检查的手术.
- 评估手术前/手术后的呼吸系统参数,发病率和死亡率.
主要成果:
- 在1秒内强制呼气体积 (10.07%) 和扩散能力 (4.74%) 中观察到显著改善.
- 平均残留体积减少了49.2%,呼吸障碍改善了1.84个点 (p < .001).
- 一个90天死亡率;20名患者出现了长时间的空气泄漏.
结论:
- 对于不适合BLVR的肺气患者来说,LVRS是一种安全有效的选择.
- 在这种患者群体中,LVRS提供了实质性的功能增长.
- 长期跟踪对确认LVRS的持续益处至关重要.
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