在住院时预测COVID-19严重性风险的临床特征
Dikshant Sagar1,2, Tanima Dwivedi3, Anubha Gupta4
1Computer Science, Indraprastha Institute of Information Technology - Delhi, Delhi, IND.
Cureus
|May 1, 2024
概括
一种可解释的人工智能 (AI) 模型,CoSP,使用患者入院时的临床数据准确预测COVID-19的严重程度. 这种工具有助于早期干预和资源配置,以改善患者的治疗结果.
科学领域:
- 医疗信息学 医疗信息学
- 医疗保健中的人工智能
- 流行病学 流行病学
背景情况:
- 在全球范围内,COVID-19疫情造成了显著的死亡率和发病率.
- 早期识别高风险患者对于有效管理和资源分配至关重要.
- 在住院时预测疾病严重程度有助于及时做出治疗决策.
研究的目的:
- 开发一个可解释的AI模型来预测COVID-19的严重程度.
- 在入院时利用临床特征进行严重性风险评估.
- 将患者分为无症状,轻度,中度和严重风险组.
主要方法:
- 使用了来自7416名COVID-19患者的64个人口统计和实验室特征的数据集.
- 一个分层的人工智能模型,CoSP (COVID-19严重程度预测器) 被开发出来.
- 用沙普利分析来确定模型的可解释性.
主要成果:
- CoSP实现了AUC-ROC为0.95,AUPRC为0.91,加权F1得分为0.83.
- 该模型确定了19个预测COVID-19严重程度的关键特征.
- 与其他ML方法相比,CoSP表现出卓越的性能和可解释性.
结论:
- 由人工智能驱动的CoSP模型有效地预测了COVID-19的严重程度.
- 这种工具可以促进早期干预和个性化治疗策略.
- CoSP有助于优化疫情期间医院资源分配.
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