接触力对使用焦点导管的脉冲场除结果的影响
Arwa Younis1, Pasquale Santangeli1, Kara Garrott2
1Cardiac Electrophysiology Section, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH (A.Y., P.S., C.T., S.Y.W., A.A.H., S.N., H.N., T.T., M.K., J.S., W.I.S., O.M.W.).
Circulation. Arrhythmia and electrophysiology
|May 1, 2024
概括
脉冲场 (PF) 除产生比射频除更广泛的心房病变. 接触力 (CF) 显著增加了PF损伤深度,为心律失常治疗提供了一种新方法.
科学领域:
- 电子生理学 电子生理学
- 医疗器械 医疗器械
- 心血管研究研究心血管研究
背景情况:
- 传统的焦点射频导管可以适应脉冲场 (PF) 或射频 (RF) 能量传递.
- 接触力 (CF) 反为心律失常治疗提供了更大的灵活性.
- 关于CF在PF切除过程中对病变形成的影响的数据有限.
研究的目的:
- 为了比较PF和RF能量模式之间的心房病变形成.
- 为了研究在PF切除过程中变化的接触力 (CF) 水平对病变尺寸的影响.
主要方法:
- 在实体猪模型中使用了一种试验式双能焦点导管.
- 实验I:使用RF和PF能量创建了点对点的间隙线.
- 实验II:使用低,中,高CF水平的PF创建了离散的心室病变.
主要成果:
- 无论是RF还是PF能量都造成了完整的,透视性心房病变.
- 与RF相比,PF除导致心房病变线明显更宽 (P<0.01).
- 在PF切除过程中较高的CF水平与损伤深度 (r=0.82,P<0.001) 和体积 (r=0.55,P<0.001) 的增加相关.
结论:
- 使用焦点,CF感应导管的新型PF剥离波形创造了比RF更广泛的外围心脏病变.
- 损伤深度在PF切除过程中与CF有显著的正相关性.
相关概念视频
Calculation of Electric Flux
Consider the electric field of an oppositely charged, parallel-plate system and an imaginary box between those plates. Let the bottom face of the box be ABCD, and the top face be FGHK. The electric field between the plates is uniform and points from the positive plate toward the negative plate. The calculation of this field's flux through the box's various faces shows that the net flux through the box is zero. Why does the flux cancel out here?
Motional Emf
Magnetic flux depends on three factors: the strength of the magnetic field, the area through which the field lines pass, and the field's orientation with respect to the surface area. If any of these quantities vary, a corresponding variation in magnetic flux occurs. If the area through which the magnetic field lines are passing changes, then the magnetic flux also changes. This change in the area can be of two types: the flux through the rectangular loop increases as it moves into the magnetic...
Induced Electric Fields
The fact that emfs are induced in circuits implies that work is being done on the conduction electrons in the wires. What can possibly be the source of this work? We know that it’s neither a battery nor a magnetic field, as a battery does not have to be present in a circuit where current is induced, and magnetic fields never do any work on moving charges. The source of the work is in fact an electric field that is induced in the wires. For example, if a stationary conductor is placed in a...
Induced Electric Fields: Applications
An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
Controlled-Current Coulometry: Overview
Controlled current coulometry, also known as amperostatic coulometry, is a technique used in electrochemical analysis to measure the quantity of a substance through the controlled passage of current. It involves the application of a constant current to an electrochemical cell containing the analyte of interest. As the current flows through the cell, the analyte undergoes a redox reaction at the electrode surface, resulting in a charge transfer. By monitoring the time required for a certain...
Field Effect Transistor
Field-effect transistors (FETs) are integral to electronic circuits and distinguished by their three-terminal setup: the gate, drain, and source. These transistors operate as unipolar devices, which utilize either electrons or holes as charge carriers, in contrast to bipolar transistors, which use both types of carriers. The primary function of the FET is to modulate the flow of these carriers from the source to the drain through a channel. The voltage difference between the gate and source...


