在额外胸部恶性瘤中,中质粒状/类似肉类淋巴腺病的重要性
Serhat Erol1, Aslıhan Gurun Kaya1, Fatma Arslan1
1Department of Chest Diseases, Ankara University School of Medicine, Ankara, Turkey.
Diagnostic cytopathology
|May 1, 2024
概括
患有胸外恶性瘤 (ETM) 的患者的样反应 (SLR) 表明转移的风险较低. 颗粒状中枢性淋巴腺病变 (MLN) 具有高负预测值,这表明随访成像足够.
科学领域:
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
- 病理学 病理学 病理学
背景情况:
- 胸外恶性瘤 (ETM) 可以呈现出类似类反应 (SLR),一种在排水淋巴结中形成的粒状淋巴腺病的一种形式.
- 在ETM患者中SLR的临床意义,特别是其与转移的关联,需要研究.
研究的目的:
- 调查ETM和粒状中枢淋巴腺病变 (MLN) 患者的临床过程和复发率.
- 为了确定SLR是否是ETM患者即将发生转移的迹象.
主要方法:
- 对已知ETM患者进行EBUS-TBNA以进行分期或复发检测的回顾性观察研究 (2011-2023年).
- 纳入标准:患有粒状MLN的患者.
主要成果:
- 在41名患者中,有33人被诊断患有SLR;乳腺和结直肠癌是最常见的.
- 颗粒状MLN转移的负预测值 (NPV) 为97.05%.
- 只有一个SLR患者在随访期间表现出淋巴结进展.
结论:
- 在ETM患者中,粒状MLN可能是由肉病,结核病,药物反应或SLR引起的.
- 在ETM患者中,SLR显示了转移的高NPV.
- 对这些患者来说,随访成像是确认活检的合理替代方案.
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