十多年来,街头抓获的狂喜药的质量转变:巴西里约热内卢的一个案例研究
Ananda da Silva Antonio1, Gleicielle Tozzi Wurzler1, Cecília de Andrade Bhering1
1Instituto de Química, Núcleo de Análises Forenses (NAF) - Laboratório de Apoio Ao Desenvolvimento Tecnológico (LADETEC), Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Journal of forensic sciences
|May 1, 2024
概括
在里约热内卢,对狂喜药片的化学指纹检测揭示了正在演变的药物成分和切割剂. 这种分析通过追踪非法药物趋势和识别使用模式,有助于执法和公共卫生.
科学领域:
- 法医化学 法医化学
- 非法药物分析 非法药物分析
- 公共卫生监督 公共卫生监督
背景情况:
- 非法毒品市场是充满活力的,药物成分和伪造剂经常发生变化.
- 了解这些变化对于执法情报和公共卫生干预至关重要.
- 狂喜药片经常被误解,由于成分的变化,可能会带来未知的健康风险.
研究的目的:
- 从2012年到2021年在里约热内卢查获的狂喜药片进行化学指纹检查.
- 识别主要成分,切割剂和潜在的使用模式.
- 提供支持警察情报和公共卫生战略的数据.
主要方法:
- 使用了气色谱-高分辨率质谱法 (GC-HRMS) 和减弱总反射里埃变换红外光谱法 (ATR-FTIR).
- 药片样本经过准备,包括称重,提取,稀释和酸化.
- 分析的重点是确定化学配置文件和量化成分.
主要成果:
- 检测到的主要物质是3,4-甲基enedioxymethamphetamine (MDMA) 和clobenzorex.
- 其他物质如MDA,MDEA和2C-B的发现频率较低.
- 确定了27种不同的切割剂组合,包括咖啡因,,麻醉剂.
- 克洛本佐雷克斯占主导地位的样本在高速公路附近普遍存在,这表明卡车司机使用它.
- 里约热内卢的大型事件与狂喜的化学指纹的变化相关.
结论:
- 化学分析提供了对不断变化的非法药物领域的关键见解.
- 调查结果支持执法部门在重大事件期间预测市场行为,并确定贩运路线.
- 数据通过描述药物含量和潜在风险来帮助公共卫生倡议.
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