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Updated: Jun 27, 2025

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植物性饮食和前列腺癌男性的疾病进展
Vivian N Liu1,2, Erin L Van Blarigan1,3, Li Zhang1,4
1Department of Epidemiology and Biostatistics, University of California, San Francisco.
JAMA network open
|May 1, 2024
概括
在前列腺癌诊断后采用植物性饮食可能会降低癌症进展的风险. 这种饮食模式与前列腺癌患者的更好的健康结果有关.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 植物性饮食为健康和环境带来好处,包括潜在的致命前列腺癌的初级预防.
- 有限的数据存在于诊断后植物性饮食模式对前列腺癌结果的影响.
研究的目的:
- 研究诊断后植物性饮食模式与前列腺癌进展风险之间的关联.
- 检查这些饮食模式与前列腺癌特异性死亡率之间的关系.
主要方法:
- 一项纵向观察队列研究包括2062名活检证明非转移性前列腺癌的男性.
- 使用经过验证的食物频率问卷 (FFQ) 评估饮食模式,计算整体植物性饮食指数 (PDI) 和健康植物性饮食指数 (hPDI) 评分.
- 分析了2022年8月至2023年4月的数据,FFQ后的中位数随访时间为6.5年.
主要成果:
- 与最低五位数相比,PDI最高五位数的男性表现出进展风险降低了47% (HR,0.53;P趋势=.003).
- HPDI与整体进展风险没有显著关联.
- 在格里森等级7或更高的男性中,最高的hPDI五分位数与55%的进展风险降低有关 (HR 0.45;P趋势 = .01).
结论:
- 诊断后植物性食品的摄入量较高与前列腺癌进展风险降低有关.
- 营养评估和咨询可能对前列腺癌患者有益,以促进健康的饮食习惯和整体幸福感.
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