生殖器疹的患病率和抗病毒治疗
Purva Jain1, Alan Embry2, Brent Arakaki1
1From the Aetion, Inc., New York City, NY.
Sexually transmitted diseases
|May 1, 2024
概括
生殖器疹影响了美国人口的很大一部分,在年轻人和女性中患病率最高. 大多数患者接受这种常见的性传播疾病的插曲性抗病毒治疗.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 生殖器疹是一种常见的性传播感染 (STI),由简单疹病毒引起,缺乏最近的美国人口数据.
- 有限的当代流行病学数据阻碍了对生殖器疹患病率和治疗模式的理解.
研究的目的:
- 提供美国性器疹流行率的全国代表性估计.
- 使用大型医疗保险索赔数据库分析生殖器疹的治疗模式.
主要方法:
- 一项使用HealthVerity (2019-2021) 的行政索赔数据的观察性队列研究.
- 对生殖器疹和复发性生殖器疹的原始和年龄/性别标准化流行率的计算.
- 在接受治疗的患者中估计抗病毒疗法 (插曲性与抑制性) 的分布.
主要成果:
- 生殖器疹的标准化患病率在每10万人/年 (2019-2021) 中从236-280不等.
- 在25-29岁的个体,女性和有艾滋病毒感染史的人群中观察到的最高患病率.
- 三分之二的患有生殖器疹的患者接受了抗病毒治疗,主要是间歇性治疗 (80%).
结论:
- 生殖器疹和复发性生殖器疹在美国构成了相当大的公共卫生负担.
- 年轻成年人,妇女和免疫受损个体的患病率最高.
- 大约三分之二的受影响个体每年接受抗病毒治疗.
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