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Updated: Jun 27, 2025

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
28:15

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Published on: July 28, 2010

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微卫星的不稳定性在不匹配修复熟练的结直肠癌:临床特征和潜在的分子机制

Yun Xu1, Kai Liu2, Cong Li1

  • 1Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, PR China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.

EBioMedicine
|May 1, 2024
PubMed
概括

不匹配修复 (dMMR) 和高微卫星不稳定性 (MSI-H) 的缺陷是结直肠癌 (CRC) 的关键生物标志物. 这项研究确定了一个独特的pMMR/MSI-HCRC亚组,具有独特的免疫特征和MSH3突变,提供了新的诊断潜力.

关键词:
结肠直肠癌是一种癌症.诊断生物标志物 诊断生物标志物微卫星的不稳定性是微观的纠正不匹配的修复方法预测建模的预测建模.

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