Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Action Potential01:31

Action Potential

7.9K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they...
7.9K
The Role of Ion Channels in Neuronal Computation01:19

The Role of Ion Channels in Neuronal Computation

3.2K
A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....
3.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Design of efficient high-order immersed metagratings using an evolutionary algorithm.

Optics express·2026
Same author

Incorporating softmax in psychophysical detection models for normal and electric hearing.

MethodsX·2026
Same author

The current status and future of using computational models to individually optimise cochlear implant stimulation.

Expert review of medical devices·2026
Same author

Leveraging spatial cues from cochlear implant microphones to efficiently enhance speech separation in naturalistic listening scenes.

Scientific reports·2025
Same author

The Influence of Speech Material, Intelligibility, and Masker Type on the Pupil Dilation Response in Cochlear Implant Users.

Ear and hearing·2025
Same author

From spikes to speech: NeuroVoc - A biologically plausible vocoder framework for auditory perception and cochlear implant simulation.

Hearing research·2025

相关实验视频

Updated: Jun 27, 2025

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

1.7K

生物物理学启发的尖峰速率适应用于计算效率高的现象神经模型.

Jacob de Nobel1, Savine S M Martens2, Jeroen J Briaire2

  • 1Leiden Institute of Advanced Computer Science, Niels Bohrweg 1, Leiden, Netherlands.

Hearing research
|May 1, 2024
PubMed
概括

新的PHAST+模型有效地模拟了听觉神经纤维对耳植入物电刺激的反应. 它改进了先前用于延长神经活动的模型,使实时模拟成为可能.

关键词:
听觉神经是听觉神经的一部分.耳植入物可以使用耳植入物.进化算法是一种进化算法.神经模型的神经模型优化优化 优化优化升率调整的适应方法

更多相关视频

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.5K
Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
08:48

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

Published on: September 5, 2012

11.9K

相关实验视频

Last Updated: Jun 27, 2025

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

1.7K
Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
08:08

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond

Published on: June 24, 2015

11.5K
Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
08:48

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

Published on: September 5, 2012

11.9K

科学领域:

  • 计算神经科学是一种神经科学.
  • 生物物理学的生物物理.
  • 听觉神经生理学 听觉神经生理学

背景情况:

  • 听觉神经纤维的行为对于了解耳植入物的功能至关重要.
  • 模拟神经对电刺激的反应是计算密集的.
  • 现有的模型在准确地表示长时间的神经活动方面面临挑战.

研究的目的:

  • 介绍和评估用于模拟听觉神经纤维反应的PHAST+模型.
  • 提高扩展刺激持续时间模拟的计算效率.
  • 在耳植入物研究中提高神经反应建模的准确性.

主要方法:

  • 开发了PHAST+模型,其中包含了一个漏洞集成器,用于适应和适应.
  • 利用计算框架模拟听觉神经纤维行为.
  • 用各种电刺激与单纤维动物数据对模型进行验证.

主要成果:

  • PHAST+在各种刺激中表现出有效性,包括可变幅度和速率脉冲列车.
  • 该模型与其前身PHAST相比显示出更高的性能,特别是在长时间的神经反应方面.
  • PHAST+准确地预测了尖峰速率衰变,并且在载体强度和适应性测量方面表现良好.

结论:

  • PHAST+提供了一种计算高效和准确的方法,用于模拟神经对耳植入物刺激的反应.
  • 该模型在长时间内执行实时模拟的能力对未来的研究有重大影响.
  • PHAST+促进了对用于耳植入物的新型语音编码策略和心理物理实验的评估.