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Updated: Jun 27, 2025

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拉斯G12C抑制剂:三只鸟用一块石头

Tessa Seale1, Sandra Misale1

  • 1Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland.

Cancer discovery
|May 1, 2024
PubMed
概括

KRAS G12C 抑制剂表现出多种结合能力,共地向其他 RAS 蛋白质,如 NRAS 和 HRAS. 索托拉西布成为NRAS G12C突变的强有力的抑制剂.

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