来自巴西的有毒蓝藻细菌的新记录:探索它们的发生和地理位置
Thaíssa Giovanna Valverde Campos1, Watson A Gama2, Vanessa Geraldes3
1University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil.
The Science of the total environment
|May 1, 2024
概括
菌有害藻类繁殖 (CyanoHABs) 是一个全球性的威胁. 这项研究审查了巴西的CyanoHABs和毒素,发现49%的菌株有毒,有许多未识别的化合物,强调迫切需要监测.
科学领域:
- 环境科学环境科学
- 毒理学 毒理学 毒理学
- 微生物学 微生物学
背景情况:
- 菌有害藻类繁殖 (CyanoHABs) 对生态系统和公共健康构成重大全球风险.
- 自1993年以来,巴西经历了众多CyanoHAB事件,其中包括1996年的著名事件.
- 卡鲁阿鲁综合征 卡鲁阿鲁综合征
- 在2015-2016年干旱期间,疫情爆发和萨克西托克素增加.
研究的目的:
- 对巴西的毒素和CyanoHAB物种分布进行深入的审查.
- 详细说明目前用于检测毒素的检测方法.
- 调查巴西蓝菌株的毒性,并确定产生的毒素.
主要方法:
- 分析了1993年至2021年的421起CyanoHAB事件.
- 使用ELISA,生物测试,HPLC和LC-MS进行毒素分析.
- 对37种隔离的蓝菌株进行毒性测试,以对抗Artemia salina,并使用LC-MS和GNPS分析进行毒素识别.
主要成果:
- 49%的测试的蓝菌株表现出毒性.
- 通过GNPS进行LC-MS分析,在巴西菌株中确定了6个毒素组.
- 75%的有毒提取物含有未识别的化合物,这表明需要进一步研究.
结论:
- 毒素的产生在物种之间和随着时间的推移而变化,超出了微囊的范围.
- 迫切需要对蓝菌进行持续监测,并将蓝毒素管理纳入公共卫生政策.
- 进一步的研究至关重要,以了解这些生物对水质和公共健康的全部影响.
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