对T2-3胸膜恶性瘤进行修改的子体视频辅助胸腔镜手术胸膜切除术的术后结果和生存率:一项回顾性比较研究
Xinyu Yang1, Jiahao Jiang1, Yongqiang Ao1
1Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China; Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
概括
经过修改的子体视频辅助胸腔镜手术 (thymectomy) 与中部胸膜切除相比,在局部发达的胸膜恶性瘤中提供了改善的外科治疗结果. 这种最少的侵入性方法证明了安全性和有效性,具有类似的瘤学结果.
科学领域:
- 胸部外科手术 胸部外科手术
- 最少侵入性手术的方法
- 在瘤学瘤学.
背景情况:
- 局部侵入性胸膜恶性瘤带来了外科手术的挑战.
- 经过修改的子体视频辅助胸腔镜外科手术胸切除术 (svats) 是传统中枢切除术的潜在替代方案.
- 之前的研究表明,SVAT对于胸膜恶性瘤的可行性.
研究的目的:
- 为了比较SVATs的外科手术和瘤结局与中枢胸切除术的结果.
- 评估SVAT治疗局部发达的胸膜恶性瘤的安全性和有效性.
- 确定最少侵入性方法的潜在好处.
主要方法:
- 分析了221名患有T2-3胸膜恶性瘤的患者的前性维护数据库.
- 倾向性得分匹配 (1:1) 用于平衡患者组.
- 术后的数据,包括手术持续时间,血液损失和并发症,在SVAT和中部椎切除组之间进行了比较.
主要成果:
- 施瓦茨组的手术时间显著缩短,血液流失较少,排水时间较短,住院时间较短.
- 在SVATS组中观察到的术后并发症较少 (5.6%与23.6%相比).
- 完全切除率和生存分析 (无复发和整体生存) 在两组之间都相似.
结论:
- 经过修改的子体视频辅助胸腔镜手术 (胸膜切除术) 对T2-3胸膜恶性瘤是安全有效的.
- 头可以成为中枢骨切除术的可行替代方案,适用于局部发达胸膜疾病的选定患者.
- 需要进一步的前性研究来评估长期生存结果.
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