吸烟相关的间歇性肺病:历史视角和21世纪的进展
Sanjay Mukhopadhyay1, Irene Sansano2
1Department of Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
吸烟会导致癌症以外的肺部损伤,包括间歇性纤维化. 识别这些与吸烟相关的间歇性肺病是了解患者病情的关键.
科学领域:
- 肺部病理学 肺部病理学
- 病理学 病理学 病理学
背景情况:
- 吸烟与肺癌,肺气和慢性支气管炎有关.
- 吸烟还会导致亚临床和临床组织学肺部变化,如色素性巨细胞,间歇性纤维化和朗格汉斯细胞增殖.
- 这些吸烟引起的肺部异常通常被称为"吸烟相关的间歇性肺部疾病".
研究的目的:
- 审查有关吸烟相关肺部异常的现代理解.
- 突出吸烟相关间歇性纤维化在这个领域的重要性.
主要方法:
- 关于吸烟相关间歇性肺病的现代概念的文献综述.
- 综合当前关于组织学变化及其临床影响的知识.
主要成果:
- 关于吸烟引起的肺部变化,除了常见的吸烟相关疾病之外,还存在广泛的共识.
- 组织学变化包括色素性巨细胞,间歇性纤维化和朗格汉斯细胞增殖.
- 这些变化可以是亚临床的,也可以在临床上表现为成像异常.
结论:
- 对吸烟相关的间歇性纤维化病的认知已经大大提高了对这些肺部疾病的理解.
- 对于"与吸烟有关的间歇性肺病",需要进一步的研究和一致的术语.
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