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Updated: Jun 27, 2025

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
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Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

Published on: October 17, 2013

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[基于纳米技术的透皮制剂的开发及其药物输送途径的阐明]

Hiroko Otake1, Noriaki Nagai1

  • 1Faculty of Pharmacy, Kindai University.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
|May 1, 2024
PubMed
概括

薄荷醇通过使拉洛西芬纳米颗粒能够穿透皮肤来增强通过皮肤传递的药物.

关键词:
药物输送是药物输送的过程.细胞内的形成 细胞内的形成纳米颗粒是一种纳米粒子.通过皮肤的配方.

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
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Drugs must traverse multiple biological barriers, such as multi-layered skin, single-layered intestinal epithelium, and the plasma membrane, to reach their target sites within the body. The plasma membrane, a highly structured composite of phospholipids, carbohydrates, and proteins, is the cell's protective boundary, facilitating selective substance exchange.
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