睡眠剥夺对与食物相关的帕夫洛夫仪器转移的影响:一个随机交叉实验
1Room 664, 6/F, Department of Psychology, The Jockey Club Tower, Centennial Campus, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong SAR. chanwais@hku.hk.
Scientific reports
|May 1, 2024
概括
睡眠不足并没有增加提示引起的食物寻找,与假设相反. 睡眠障碍损害了有条件的寻找食物的反应,这表明睡眠会影响食欲调节机制.
科学领域:
- 行为神经科学 行为神经科学
- 睡眠科学 睡眠科学
- 肥胖研究的研究.
背景情况:
- 睡眠不足与肥胖风险增加有关.
- 机制可能涉及加剧的提示驱动的寻找食物,覆盖腹信号.
- 之前的动物研究表明,睡眠障碍会影响食欲.
研究的目的:
- 调查是否总睡眠不足 (TSD) 与正常睡眠时间 (NSD) 相比,增强了提示引起的食物寻找.
- 为了检查睡眠在帕夫洛夫-仪器转移 (PIT) 效应中的作用.
- 了解睡眠对动机性饮食行为的影响.
主要方法:
- 这是一项针对96名成年人进行的个体内随机交叉实验.
- 一晚正常睡眠时间 (NSD) 与总睡眠剥夺 (TSD) 的比较.
- 利用Pavlovian-instrumental transfer (PIT) 范式来测量在和不状态下寻找食物对有条件线索的反应.
主要成果:
- 睡眠状况,线索和和对寻找食物反应的相互作用是显著的.
- 有条件的线索在正常睡眠时间 (NSD) 中增强了寻找食物的反应,但不是完全睡眠剥夺 (TSD).
- 在参与者在两种睡眠条件中都达到腹后,这种提示引起的增强消失了.
结论:
- 这些发现与睡眠不足可以增强提示驱动饮食的假设相矛盾.
- 睡眠障碍似乎会损害,而不是增强,有条件的食欲行为,与动物研究一致.
- 这项研究为睡眠在帕夫洛夫仪器转移和动机性饮食中的作用提供了新的证据.
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