一项基于应用程序的对2型糖尿病患者身体活动和血糖控制的应用程序干预的随机对照试验
Gyuri Kim1, Seohyun Kim2, You-Bin Lee1
1Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-Ro, Gangnam-Gu, Seoul, 06351, Republic of Korea.
BMC medicine
|May 1, 2024
概括
智能手机应用程序干预并没有显著增加2型糖尿病患者的每日步骤. 然而,它在一些人身上显示出改善血糖控制 (HbA1c) 的潜力,特别是那些基线水平较高的人.
科学领域:
- 数字健康数字健康
- 代谢疾病 代谢疾病
- 身体活动干预措施
背景情况:
- 2型糖尿病 (T2D) 的管理通常需要改变生活方式,包括增加体力活动.
- 智能手机应用程序提供了一个提供健康干预和监测患者进展的平台.
- 与移动应用程序集成的个人健康记录 (PHR) 可能有助于患者参与自我管理.
研究的目的:
- 评估智能手机基于PHR应用程序的体育活动鼓励干预对T2D患者的步数,血糖控制和体重的影响.
- 评估通过智能手机应用程序传递的个性化激励性短信在促进身体活动方面的有效性.
- 分析二次结果,包括HbA1c,禁食葡萄糖和体重的变化.
主要方法:
- 一项为期12周的随机对照试验,涉及患有T2D的超重或肥胖患者.
- 参与者被分配到使用智能手机PHR应用程序的对照组或使用应用程序添加激励性短信的干预组.
- 主要结局:每天步数的变化;次要结局:HbA1c,禁食葡萄糖和体重的变化.
主要成果:
- 干预组和对照组之间整体每日步数增加没有显著差异.
- 在干预组中,在基线步数低于7500的参与者中,观察到每日步数的显著增加.
- 与对照组相比,干预组在12周内显示HbA1c显著降低,特别是在基线HbA1c≥7.5%的患者中.
- 两组患者在第24周体重显著减轻,两组之间没有显著差异.
结论:
- 基于应用程序的动机干预体育活动并没有显著增加T2D患者的整体每日步数.
- 该干预措施对特定亚组的血糖控制 (HbA1c) 产生了积极影响.
- 需要进一步的研究来优化数字健康干预措施,以持续体力活动和改善T2D中的代谢结果.
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