空气污染和流感:系统审查和元分析
1Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410013, Hunan, China.
Iranian journal of public health
|May 2, 2024
概括
空气污染,包括颗粒物 (PM2.5,PM10),二氧化 (NO2) 和二氧化硫 (SO2),与流感风险增加有关. 在这项研究中,一氧化碳 (CO) 和臭氧 (O3) 没有显著的关联.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 传染病流行病学 传染病流行病学
背景情况:
- 流感是一个主要的全球公共卫生问题,建立了全球监测系统.
- 空气污染已成为一个重要的全球健康问题,越来越多的证据将其与呼吸系统疾病联系起来.
研究的目的:
- 进行一项元分析,研究各种空气污染物暴露与流感发病风险之间的关联.
- 确定可能作为流感风险因素的特定空气污染物.
主要方法:
- 在多个数据库 (PubMed,科学网,CNKI等) 进行了全面的文献搜索. 在2022年11月15日之前.
- 与流感和空气污染物 (PM2.5,PM10,NO2,SO2,CO,O3) 相关的关键词被用于搜索策略.
- 在19项选定的研究中,使用R编程语言 (R4.2.1) 进行了元分析.
主要成果:
- 在暴露于颗粒物 (PM2.5,PM10),二氧化 (NO2) 和二氧化硫 (SO2) 和流感发病风险之间发现了显著的关联.
- 对于PM2.5,NO2,PM10和SO2的相对风险分别为1.0221,1.0395,1.007和1.0352.
- 在暴露于一氧化碳 (CO) 或臭氧 (O3) 和流感发病率之间没有发现显著的关系.
结论:
- 暴露于PM2.5,NO2,PM10和SO2与流感有显著的关联,可以被认为是危险因素.
- 暴露于CO和O3和流感之间的潜在关联需要进一步调查.
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