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老年人双极性障碍的治疗:一篇综述
Nemanja Ljubic1, Bianca Ueberberg1, Heinz Grunze1
1Bereich Forschung & Wissenschaft, LWL-Klinik, Marsbruchstr. 179, 44287 Dortmund, Germany (Ljubic, Ueberberg, Assion); Psychiatrie Schwäbisch Hall, Ringstraße. 1, 74523 Schwäbisch Hall, Germany (Grunze); Paracelsus Medical University, Ernst-Nathan Straße 1, 90419 Nuremberg, Germany (Grunze).
概括
老年人的双极性障碍 (BD) 尚未得到充分研究,有明显的早期和晚期发病形式. 对于和心理治疗等治疗方法的证据有限,这凸显了对老年BD进行更多研究的需要.
科学领域:
- 老年精神病学是一门精神病学专业.
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
背景情况:
- 双极性障碍 (BD) 影响0.5-1.0%的老年人群,但仍未得到充分研究.
- 在老年人中,区分新发病和复发性BD是不清楚的关于病因,过程和治疗.
- 本综述综合了关于老年 BD 流行病学,临床表现和管理的当前知识.
研究的目的:
- 提供对老年人双相情感障碍的全面概述.
- 总结有关老年人BD流行病学,临床特征和治疗的当前发现.
- 确定研究中的差距,并建议老年人BD的未来方向.
主要方法:
- 从1970年到2021年,使用相关的MeSH术语进行了Medline文献搜索.
- 搜索结果补充了交叉引用和教科书分析.
- 这篇叙事综述综合了从文献中获取的发现.
主要成果:
- 老年BD呈现出明显的早期和晚期发作的亚型,在症状和并发症上有所不同.
- 与年轻人相比,患有BD的老年人患有抑郁症更为普遍.
- 药物治疗 (,抗药,抗精神病药,抗抑郁药) 的证据稀少;ECT,心理治疗和心理社会干预措施初步显示出希望.
结论:
- 进一步的研究对于老年双相情感障碍的所有治疗方式至关重要.
- 未来的研究应该优先考虑药理学和心理社会方法,包括组合疗法.
- 物理治疗的作用,如电疗法 (ECT) 在老年人中,需要进一步研究.
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