精准医学时代的晚期肝细胞癌转化疗法:当前状况,挑战和机遇
Ming-Da Wang1, Xue-Jun Xu2, Ke-Chun Wang1
1Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University (Navy Medical University), Shanghai, China.
Cancer science
|May 2, 2024
概括
转化疗法通过允许手术改善晚期肝细胞癌 (HCC) 的存活率. 解决患者选择和治疗时间方面的争议是未来HCC治疗进展的关键.
科学领域:
- 肝胆道手术是肝胆道的手术.
- 医学瘤学 医学瘤学
- 胃肠病学 胃肠病学
背景情况:
- 肝细胞癌 (HCC) 的死亡率很高,通常在无法切除的阶段被诊断出来.
- 通过全身和局部区域疗法,先进的HCC管理得到了改进,使转化疗法成为可能.
研究的目的:
- 审查目前的策略和临床经验转化疗法在先进的HCC.
- 突出未解决的问题和HCC转化疗法的未来方向.
主要方法:
- 这项研究是对HCC转化疗法现有文献的叙事性综述.
- 它综合了当前的策略,临床经验和现场争议.
主要成果:
- 结合局部区域和全身疗法的多式疗法可以提高瘤衰退阶段和手术切除能力.
- 高转化率对于晚期HCC患者的长期存活至关重要.
结论:
- 转化疗法是高级HCC存活的主要途径,但候选人选择,治疗方案制定和时间的挑战仍然存在.
- 完善HCC转化疗法的协议和研究对于未来的进步至关重要,特别是在精密医学领域.
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