在COPD和CHF受试者中,最大和次最大功率的可比呼吸系统低效:一种创新的方法
Gerson Gatass Orro de Campos1, Leandro Steinhorst Goelzer1, Tiago Rodrigues de Lemos Augusto1
1Universidade Federal de Mato Grosso do Sul (UFMS) - Hospital Maria Aparecida Pedrossian (HUMAP), Laboratório de Fisiopatologia Respiratória (LAFIR), Campo Grande, MS - Brasil.
一种新的通风效率 (ηEV ̇) 方法在慢性心力衰竭和COPD患者中显示了类似的结果,与传统的V ̇E-V ̇CO2测量不同. 这种方法有助于比较各种心肺疾病.
科学领域:
- 心肺运动生理学 运动生理学
- 临床医学 临床医学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 过度通风的传统评估依赖于分钟通风/二氧化碳输出 (V ̇E-V ̇CO2) 关系.
- 一个新的指标,通风器效率 (ηEV ̇),为评估通风器功能提供了另一种方法.
研究的目的:
- 测试该假设,呼吸器效率 (ηEV ̇) 水平在慢性心力衰竭 (CHF) 和慢性阻塞性肺病 (COPD) 患者之间是可比的.
- 为了将新型的 ηEV ̇度量与已建立的 V ̇E-V ̇CO2 斜率进行比较,并在这些患者群体中进行拦截.
主要方法:
- 19名COPD患者和19名CHF患者接受了肺功能测试,心声图和心肺运动测试.
- 该研究分析了整个炼期间的V ̇E-V ̇CO2和 ηEV ̇值,以及最大值的90%和75%的值.
- 统计学意义被设定为p<0.05.05.
主要成果:
- 慢性肺炎和慢性心血管疾病组表现出类似的人口统计,BMI和峰值V ̇O2.2.
- 在COPD和CHF组之间的V ̇E-V ̇CO2斜率和截面 (p<0.05) 中发现了显著的差异.
- 平均 ηEV ̇值在两组之间是可比的 (p=0.462),在不同运动强度 (r>0.850) 上观察到 ηEV ̇的强相关性.
结论:
- 呼吸器效率 (ηEV ̇) 度量为比较COPD和CHF等不同心肺疾病的患者提供了有价值的工具.
- 尽管有不同的病理,但 ηEV ̇可能比V ̇E-V ̇CO2更强大,反映了潜在的生理相似性,包括COPD的呼吸系统限制.
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