计算机断层扫描评估的皮症预测了移植候选人的死亡率
Harun Coban1, Dilek Barutcu Atas, Murat Tugcu
1From the Department of Internal Medicine, Division of Nephrology, Marmara University School of Medicine, Istanbul, Turkey.
概括
低肌肉质量或 Sarcopenia 在等待移植的末期病患者中明显更常见. 这种情况是移植后死亡的独立风险因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 在慢性病 (CKD) 中,肉类是普遍存在的,并且与死亡率有关.
- 在移植等待名单上的末期病 (ESRD) 患者中调查性症至关重要.
研究的目的:
- 为了确定等待移植的ESRD患者中症的患病率.
- 评估肉类与预后营养指数 (PNI),C反应蛋白与白蛋白比率 (CRP/Alb),心血管事件和死亡率的关联.
主要方法:
- 包括162名ESRD患者和87名年龄相匹配的健康对照.
- 萨尔科佩尼亚是由psoas肌肉指数定义的.
- 从医疗记录中计算PNI和CRP/Alb比率.
主要成果:
- 与对照组相比,ESRD患者表现出较高的麻症患病率 (16.7%与3.4%) 和CRP/Alb比率,PNI较低.
- 在ESRD患者中 Sarcopenia 与较低的PNI和较高的CRP/Alb比率相关.
- 没有肉类的患者在移植后的5年生存期更好.
结论:
- 在ESRD患者中,肉症的发生率比对照患者高5倍.
- 皮症是等待移植的ESRD患者死亡的独立风险因素.
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