在患有先天性心脏病的患者中,左心房旋流及其与左心房功能之间的关系
Keita Ito1, Hideharu Oka2, Yuki Shibagaki1
1Department of Pediatrics, Asahikawa Medical University, 2-1-1-1, Midorigaoka-Higashi, Asahikawa, Hokkaido, 078-8510, Japan.
概括
在先天性心脏病 (CHD) 患者中,缺少左心房流 (LAVF) 可能表明早期的左心房功能障碍. 四维流动MRI显示,LAVF在术后心脏病患者中经常丢失,与左心房功能减弱相关.
科学领域:
- 心血管成像 - 心血管成像
- 心脏生理学 心脏生理学
- 遗传性心脏病研究 遗传性心脏病研究
背景情况:
- 四维流动MRI可视化血液流动,有助于理解左心房流 (LAVF).
- 缺乏LAVF与血栓形成和心律失常有关.
- 在先天性心脏病 (CHD) 患者中LAVF的临床意义尚未得到充分确立.
研究的目的:
- 研究患有心脏病的患者中LAVF和左心房功能之间的关系.
- 为了确定手术后心血管疾病患者的LAVF是否发生变化.
主要方法:
- 使用四维流动MRI (速度编码100厘米/秒) 来评估LAVF的存在.
- 评估左心房功能使用横心房心声学.
- 包括8名术后心脏病患者和17名健康志愿者,所有人都处于鼻节律.
主要成果:
- 在16名参与者中检测到LAVF.
- 与志愿者 (6%) 相比,术后心脏病患者更有可能缺乏LAVF (78%).
- 没有LAVF的参与者表现出明显较低的左心房外射分数,储和导管功能.
结论:
- 左心房流 (LAVF) 发生在静脉缩的晚期,可能受到储功能的影响.
- 许多术后心脏病患者表现出LAVF的丧失.
- 缺少LAVF可能意味着早期的左心房功能障碍是由于心脏病的重塑.
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