[动脉高血压患者的认知障碍]
V V Zakharov1, P A Chernousov1, K A Vekhova1
1Sechenov First Moscow Medical University (Sechenov University), Moscow, Russia.
概括
动脉高血压 (AH) 是中风和血管认知障碍 (VCI) 的主要危险因素. 通过神经心理评估和神经成像进行早期检测,再加上抗高血压和神经保护性治疗,如乙基甲基氧氨酸酸盐 (mexidol),对于管理大脑损伤至关重要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
背景情况:
- 动脉高血压 (AH) 是心血管疾病的主要危险因素.
- 高血压引起的脑损伤可以表现为中风或血管认知障碍 (VCI).
- 在AH患者中,VCI是目标器官损伤的关键指标.
研究的目的:
- 强调在高血压患者中识别和评估VCI的重要性.
- 强调神经成像在确认认知缺陷的血管起源方面的作用.
- 讨论管理策略,包括抗高血压和神经保护疗法.
主要方法:
- 对VCI检测和严重程度评估进行神经心理评估.
- 神经成像技术以确认认知障碍的血管病因.
- 对包括抗高血压和神经保护剂在内的治疗干预措施的审查.
主要成果:
- 神经心理学评估对于确定AH中的VCI至关重要.
- 神经成像证实了认知障碍的血管原因.
- 乙基甲基酸酸 (mexidol) 显示出作为神经保护剂的显著临床疗效.
结论:
- 高血压患者需要定期对VCI进行神经心理评估.
- 建议综合管理,包括抗高血压疗法和神经保护.
- 墨西多尔是一种有前途的神经保护选择,用于VCI的AH患者.
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