联邦对华盛顿州布普伦诺芬处方的影响,2012年至2022年
Fan Xiong1, Jillian Jetson1, Cheolwoo Park1
1Fan Xiong and Jillian Jetson are with the Washington State Department of Health, Tumwater, Washington. Cheolwoo Park is with the Department of Mathematical Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of South Korea. Chris Delcher is with the Institute for Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Kentucky, Lexington.
像CARA这样的联邦政策显著增加了布普伦诺芬处方,但SUPORT法案后来减少了医生处方. 由于COVID-19大流行,护士执业人员和医生助理处方率有所下降.
科学领域:
- 公共卫生 公共卫生
- 卫生政策 卫生政策
- 药物使用障碍治疗 药物使用障碍治疗
背景情况:
- 阿片类药物使用障碍 (OUD) 仍然是一个重大的公共卫生挑战.
- 布普伦诺芬是OUD治疗的关键药物.
- 联邦处方政策旨在规范并可能扩大对OUD药物的准入.
研究的目的:
- 分析联邦处方政策对华盛顿州每月布普伦诺芬处方的影响.
- 评估2012年至2022年的政策影响,包括"全面成和康复法案" (CARA) 和"支持患者和社区法案" (SUPPORT).
- 在COVID-19大流行期间评估处方趋势.
主要方法:
- 每 1000 人口每月布普伦诺芬处方的中断时间序列分析.
- 包括华盛顿州处方监测计划中OUD的布普伦诺芬数据.
- 利用日志线性自回归模型来测量政策实施后的趋势变化.
主要成果:
- 综合性成和康复法 (CARA) 几乎使布普伦诺芬处方率增加了三倍.
- 在"促进阿片类药物恢复和治疗患者和社区法案" (SUPPORT) 颁布后,医生处方的持续下降.
- 执业护士和医生助理处方最初在CARA后增加,但在SUPPORT后的增长减少,并在COVID-19大流行期间下降.
结论:
- 在CARA立法显著提高了布普伦诺芬的处方.
- 支持法案导致医生处方趋势的下降.
- 随着COVID-19大流行,护士从业人员和医生助理的处方收益逆转,突显了对抗阿片类药物危机的持续努力的必要性.
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