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来自Tfh细胞的小细胞外囊泡通过增强B细胞反应,加剧了原诱导的关节炎的严重程度

Jian Lu1, Huimin Zhou1, Yuxuan Chen2

  • 1Department of Laboratory Medicine, Affiliated Hospital, Jiangsu University, Zhenjiang, China; Department of Immunology, Jiangsu Key Laboratory of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, China.

Journal of autoimmunity
|May 2, 2024
PubMed
概括

毛囊辅助T (Tfh) 细胞释放小细胞外囊泡 (sEV),促进B细胞反应和抗体产生. 这些Tfh衍生的sEV在小鼠中恶化自身免疫性关节炎,并且在类风湿性关节炎患者中升高.

关键词:
B 细胞 B 细胞 B 细胞在CD40L中,CD40L是CD40L.由原诱导的关节炎细胞外囊泡中的细胞外囊泡.毛囊辅助T细胞 毛囊辅助T细胞类风湿性关节炎 类风湿性关节炎 类风湿性关节炎sEVs 的使用情况.

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