估计认知性与轻度认知障碍发生率之间的关联中的性别差异
Yvonne Leung1,2,3, Ranmalee Eramudugolla1, Nicolas Cherbuin4
1School of Psychology, University of New South Wales, Sydney, New South Wales, Australia.
Gerontology
|May 2, 2024
概括
对轻度认知障碍 (MCI) 的认知性 (CR) 根据性别不同. 虽然口头智力和休活动可以保护男女,但职业技能却能保护男女.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 流行病学 流行病学
背景情况:
- 主观认知能力下降风险可能受到性别的影响,教育对女性的认知能力 (CR) 可能比男性低.
- 了解影响认知健康的特定性别因素对于开发有针对性的干预措施至关重要.
- 轻度认知障碍 (MCI) 是老年人群的一个重大问题,需要对保护因素进行研究.
研究的目的:
- 调查认知性 (CR) 代理和轻度认知障碍 (MCI) 发生率之间的性别差异.
- 检查教育程度,职业技能,口头智力和休活动如何影响男性和女性的MCI风险.
- 为了解澳大利亚基于人口的队列中的认知衰老做出贡献.
主要方法:
- 从人格和总体健康 (PATH) 通过生活研究中对1,806名参与者的分析.
- 使用离散时间生存分析来评估CR代理和MCI风险之间的关系.
- 在统计模型中调整年龄和非脂蛋白E4状态.
主要成果:
- 在CR中,性别差异主要在职业技能和MCI风险之间的关联中观察到,较低的技能对男性构成更大的风险.
- 增加休活动 (一个SD) 与男女中MCI风险降低32%,独立于教育和职业.
- 更高的口语智力得分与男性和女性MCI风险降低28%相关.
结论:
- 职业经验可能会在不同性别之间产生不同的认知性.
- 对男女来说,终身认知参与,特别是口头智力和休活动,似乎比教育或职业对MCI更有保护作用.
- 这些发现强调了考虑性别和各种认知参与策略在缓解MCI风险方面的重要性.
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