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Updated: Jun 27, 2025

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
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RNA聚合物利用危险反应进行强效的癌症免疫疗法

Hector R Mendez-Gomez1, Anna DeVries1, Paul Castillo2

  • 1University of Florida Lillian S. Wells Department of Neurosurgery, Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, FL 32610, USA.

Cell
|May 2, 2024
PubMed
概括

新的RNA脂质颗粒聚合物 (LPA) 通过重编程瘤微环境 (TME) 来克服癌症免疫治疗的极限. 这种新的方法在临床前模型和人类质母细胞瘤患者中增强了免疫细胞的流通和瘤排斥.

关键词:
大脑瘤癌症免疫疗法癌症疫苗质母细胞瘤脂质纳米粒子在 mRNA 中个性化治疗转化疗法

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