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使用马来西亚真菌Ganoderma lucidum去除废水中的药物化合物和毒理学研究

Zarimah Mohd Hanafiah¹, Wan Hanna Melini Wan Mohtar², Wan Abd Al Qadr Imad Wan-Mohtar³

¹Department of Civil Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia; Functional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.

|May 2, 2024

概括

光能有效地从废水中去除制药化合物,减少90%以上的污染物. 这种真菌显示出无毒性和可重复使用性,为污水提供了一个有希望的环保的三级处理方法.

科学领域:

环境科学环境科学
生物技术是生物技术.
水处理处理水的方法

背景情况:

由于使用量增加,制药化合物 (PC) 成为污水中的新兴污染物.
传统的废水处理厂 (STP) 难以去除这些持久污染物.
需要三级处理方法来解决废水中的药物污染问题.

研究的目的:

评估甘光 (GL) 作为一种用于从废水中去除各种制药化合物的生物剂.
为了优化处理参数,如时间,注射剂体积和PC移除的振动速度.
评估废水处理后GL的无毒性和可重复使用性.

主要方法:

光被用于处理合成废水,STP废水和医院废水 (HWW).
优化了治疗参数 (时间,注射剂体积,动速度).
使用斑马鱼胚胎 (ZFET) 暴露评估了毒性,并使用野外发射扫描电子显微镜 (FESEM) 观察了GL形态.

主要成果:

在各种水矩阵中,GL从<10%到>90%中去除了制药化合物.
在合成模型中观察到狄克洛菲纳克和瓦尔沙坦的高清除率 (>90%).
在48小时内,在真实的废水样本中,奇塔洛普拉姆和普拉诺洛尔的清除率超过80%.
GL证明对斑马鱼胚胎无毒性 (LC50 = 209.95 mg/mL),并在治疗后保持结构完整性.

结论:

光 (Ganoderma lucidum) 是一种有效且无毒的生物剂,用于从废水中去除各种制药化合物.
优化的条件 (48小时,1%的注射剂,50rpm) 促进了有效的PC去除.
GL的可重复使用性和非特异性的细胞外酶表明其作为污水和医院废水的可持续三级处理的潜力.

关键词:

这种植物叫做Ganoderma lucidum.制药化合物制药化合物污水处理污水处理有毒性有毒性

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