在西方国家,在低剂量CT上谁有肺结节的风险? 一种基于人口的方法
Jiali Cai1, Marleen Vonder1, Yihui Du1,2
1Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
The European respiratory journal
|May 2, 2024
概括
肺结节在西欧很常见,风险因素包括男性性别,年龄和吸烟史. 曾经没有吸烟,有肺癌家族史的人也有增加风险.
科学领域:
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
- 流行病学 流行病学
背景情况:
- 在一般人群中经常检测到肺结节.
- 了解风险因素对于早期发现和管理至关重要.
研究的目的:
- 在西欧一般人口中确定肺结节的危险因素.
- 量化肺结节和临床相关结节的患病率.
主要方法:
- 来自荷兰ImaLife研究的12,055名参与者 (年龄≥45岁) 的基于人口的研究.
- 低剂量胸部计算机断层扫描 (CT) 用于检测肺结节.
- 多变量逻辑回归模型确定了独立的风险因素,按吸烟状况分层.
主要成果:
- 41.8%的参与者患有肺结节;11.4%患有临床相关结节.
- 任何肺结节的危险因素包括男性性别,年龄较大,教育程度低,以前吸烟,接触石棉和慢性肺炎.
- 在从未吸烟的人中,肺癌家族史增加了结节的风险. 在吸烟者中,低教育与结节有关,而超重与负面相关.
结论:
- 肺结节和临床相关结节在西欧人口中很普遍.
- 确定的风险因素突出了需要关注的特定群体,包括从未吸烟的人,有肺癌家族史的人.
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