相关实验视频

Updated: Jun 27, 2025

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
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Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Published on: January 27, 2014

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腺体受体脱敏:当前对机制的理解

Dina Maaliki1, Aneese A Jaffa1, Suzanne Nasser1

  • 1Department of Pharmacology and Toxicology, American University of Beirut, Beirut, Lebanon (D.M.); School of Medicine, University of South Carolina, Columbia, South Carolina (A.A.J.); Keele University, Staffordshire, United Kingdom (S.N.); Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran (A.S.); Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran (A.S.); and Department of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar (A.H.E.).

Pharmacological reviews
|May 2, 2024
PubMed
概括

G蛋白结合受体 (GPCRs) 对于细胞信号传递至关重要. 它们的过度激活可能导致疾病,使得受体脱敏对于控制细胞反应和开发新疗法至关重要.

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