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生物声疗法作为长期COVID患者的治疗方法:一项前后试点研究
Colleenia Korapatti1, Lauren Vera1, Keith Miller2
1The Anxiety Relief Center, Fishers, IN, USA.
Explore (New York, N.Y.)
|May 2, 2024
概括
生物声疗法系统 (BTS) 在改善疲劳和认知困难等长期COVID症状方面表现有前途. 需要进行更大规模的试验来证实这些发现,并评估在更广泛的患者群体中可行性.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 康复医学 康复医学 康复医学
背景情况:
- 长期COVID影响了43%的COVID-19幸存者,在急性感染恢复之后出现了持续的症状.
- 长期COVID的症状与生物声疗法系统 (BTS) 已证明有效治疗的条件重叠.
- BTS是一种多式疗法,包括生物反,双耳节拍的振动声疗法和视觉内容.
研究的目的:
- 评估在长期COVID患者中对BTS进行全面随机对照试验 (RCT) 的可行性.
- 探索BTS对缓解长期COVID相关的持续症状的初步影响.
主要方法:
- 一个前后试点研究设计被用于门诊心理健康诊所.
- 患有持续COVID-19症状的参与者 (20-65岁) 被随机分配到干预 (BTS) 或对照组.
- 干预组在4周内接受了8次BTS会议;评估包括PHQ-9,GAD-7,CBS任务和长时间的COVID症状问卷.
主要成果:
- 招募了15名参与者,其中13人完成了研究 (9个干预,4个控制);招募受到Omicron变种的影响.
- 干预组在GAD-7,PHQ-9分数,认知任务 (奇偶,双重麻烦),疲劳和集中/记忆 (p <0.05) 中呈现出统计学上显著的改善.
- 开放式反完全是积极的,没有关于研究可行性的担忧.
结论:
- 在长期COVID患者中,BTS干预表明有希望的症状改善,没有不良影响.
- 一个全面的RCT被认为是可行的,这取决于修改招募策略以访问更大的患者队列.
- 这项研究的样本规模很小,因此需要进行更大规模的试验来验证这些初步发现.
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