连续运动的粒子附着在化气泡的连续运动
Fei Xu1, Yanyang Liu2, Mao Chen1
1Department of Cardiology, Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, China.
Ultrasonics sonochemistry
|May 2, 2024
概括
这项研究引入了一种新的化气泡驱动策略,用于加强心血管疾病 (CVD) 中的药物输送. 这项研究详细介绍了气泡脉冲驱动理论和实验验证,显示控制的粒子运动可以改善治疗结果.
科学领域:
- 生物医学工程 生物医学工程
- 心血管研究研究心血管研究
- 声学医学是一种声学医学.
背景情况:
- 微气泡介导的药物输送在心血管疾病 (CVD) 方面表现有前途,但需要提高效率和精度.
- 目前的方法在向和控制治疗剂运输方面面临局限性.
研究的目的:
- 为心血管疾病提出和研究一种新的空腔气泡驱动药物输送策略.
- 开发一个理论框架,并通过实验验证使用化气泡的粒子推进.
主要方法:
- 开发一个泡脉冲驱动理论,并推导时间平均推力公式.
- 在超声波场中,利用高速摄影对粒子运动的实验研究,这些运动是由空心气泡所驱动的.
- 力量的分析,包括化气泡驱动力,初级Bjerknes力,质量力和运动阻力.
主要成果:
- 洞穴气泡产生周期性脉冲推力,使液体中的粒子运动持续.
- 观察到复杂的粒子运动,包括弹射,转换,旋转和循环运动.
- 不对称的泡崩导致粒子的净推进力,克服了以前方法的局限性.
结论:
- 化泡驱动策略为心血管应用中精确和高效的药物输送提供了一个有希望的方法.
- 了解各种力量的相互作用对于优化粒子推进和治疗输送至关重要.
- 这种方法有可能显著推进针对心血管疾病的向疗法.
更多相关视频
05:31Imaging and Quantification of the Area of Fast-Moving Microbubbles Using a High-Speed Camera and Image Analysis
Published on: September 5, 2020
5.9K
11:14A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level
Published on: January 10, 2017
11.7K
相关概念视频
01:13Excess Pressure Inside a Drop and a Bubble
1.7K
The shape of a small drop of liquid can be considered spherical, neglecting the effect of gravity. This drop can further be considered as two equal hemispherical drops put together due to surface tension. The forces acting on the spherical drop are due to the pressure of the liquid inside the drop, the pressure due to air outside the drop, and the force due to the surface tension acting on the two hemispherical drops.
1.7K
01:23Steady, Laminar Flow in Circular Tubes
194
Hagen-Poiseuille flow describes a viscous fluid's steady, incompressible flow through a cylindrical tube with a constant radius R. This flow profile is often applied to understand fluid transport in narrow channels, such as capillaries. It serves as a foundational example of laminar flow. In this model, cylindrical coordinates (r,θ,z) are used to describe the radial (r), angular (θ), and axial (z) dimensions within the tube. For Hagen-Poiseuille flow, the velocity profile is...
194
01:07Laminar and Turbulent Flow
8.5K
Fluid dynamics is the study of fluids in motion. Velocity vectors are often used to illustrate fluid motion in applications like meteorology. For example, wind—the fluid motion of air in the atmosphere—can be represented by vectors indicating the speed and direction of the wind at any given point on a map. Another method for representing fluid motion is a streamline. A streamline represents the path of a small volume of fluid as it flows. When the flow pattern changes with time, the...
8.5K
01:17Steady, Laminar Flow Between Parallel Plates
175
Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
175
01:22Couette Flow
253
Couette flow represents the flow of fluid between two parallel plates, with one plate fixed and the other moving with a constant velocity. This configuration allows for a simplified analysis using the Navier-Stokes equations, which govern fluid motion under conditions of viscosity and incompressibility. For Couette flow, the assumptions include a steady, laminar, incompressible flow with a zero-pressure gradient in the flow direction. This flow type is beneficial for understanding shear-driven...
253
01:27Steady Flow of a Fluid Stream
283
Consider a control volume, such as a pipe with solid boundaries, through which fluid flows and changes direction due to the impulse exerted by the resulting force from the pipe walls. In steady flow, the mass of fluid entering the control volume at a given time, t, with velocity v1, is equal to the mass leaving after infinitesimal time dt, with velocity v2.
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...
283