H3K27me3 及时决定子宫表皮转录组重塑,从而转化为正常胚胎植入所必不可少的转化

Na Deng1, Gaizhen Li1, Leilei Zhang1

  • 1Fujian Provincial Key Laboratory of Reproductive Health Research, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361102, Fujian, China.

概括

通过H3K27me3进行表观遗传调节对于子宫受体性和胚胎植入至关重要. 破坏这种表观遗传标记会损害子宫上皮细胞的分化,导致植入失败.

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