在健康的成年人中,手脉冲波速和手脉冲过境时间的决定因素
Yung-Sheng Chen1,2,3, Wan-An Lu4, Ling-Yen Hsu5
1Department of Exercise and Health Sciences, University of Taipei, Taipei, 111, Taiwan.
Scientific reports
|May 2, 2024
概括
男性的手脉冲波速度 (hPWV) 比女性更高,hPWV和手脉冲传递时间 (hPTT) 随着年龄的增长而减少. 心率升高与hPTT降低相关.
科学领域:
- 心血管生理学心血管生理学
- 生物医学工程 生物医学工程
背景情况:
- 动脉脉冲波速度 (PWV) 是血管硬的一个关键指标.
- 手动PWV (hPWV) 和手动脉冲过渡时间 (hPTT) 提供了对外周血管健康的非侵入性评估.
研究的目的:
- 在健康成年人中研究hPWV和hPTT的临床特征.
- 确定hPWV和hPTT的决定因素,包括年龄,性别和心率.
主要方法:
- 在120名健康成年人 (60名男性,64名女性) 中测量了动脉脉冲波形和解剖距离.
- 计算hPWV是通过将辐射型体过程和中指尖之间的距离除以hPTT.
- 利用多重线性回归来分析hPWV,hPTT和人口/生理因素之间的关系.
主要成果:
- 与年龄相匹配的女性相比,男性受试者表现出明显更高的hPWV,静脉血压和脉冲压.
- 在hPTT中没有观察到显著的性别差异.
- 年龄与hPWV负相关,心率与hPTT负相关.
结论:
- 男性受试者通常比女性受试者具有更高的hPWV.
- 随着年龄的增长hPWV降低,这表明与动脉衰老有联系.
- 心率增加与hPTT较小有关,这表明潜在的生理相关性.
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