在患有血液性恶性瘤的患者中Episil®的有效性:一项比较性研究
Taeko Fukutani1, Yukio Yoshioka2, Shinpei Imori3
1Department of Oral Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami Ward, Hiroshima, 734-8553, Japan. fukutani@hiroshima-u.ac.jp.
BMC oral health
|May 2, 2024
概括
在患有血液性恶性瘤的患者中,Episil®有效治疗口腔粘膜炎,提供疼痛缓解和功能改善. 这种医疗材料证明了在多个部位出现粘膜炎的患者的特殊益处.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 口腔医学是指口腔医学.
背景情况:
- 埃皮西尔 (Episil®) 是一种不可吸收的液体医疗材料,用于治疗口腔粘膜炎.
- 关于其在血液恶性瘤中使用的数据有限.
- 这项研究通过评估Episil®在特定的血液癌症中来弥补这一差距.
研究的目的:
- 评估Episil®在治疗口腔粘膜炎中的疗效.
- 评估其对疼痛,言语和食功能的影响.
- 为了研究其在急性骨髓性白血病,恶性淋巴瘤,急性淋巴细胞白血病,多发性骨髓瘤和骨髓质疏松综合征的患者中的有用性.
主要方法:
- 一项涉及37名患有血液性恶性瘤和口腔粘膜炎的患者的研究.
- 患者在广岛红十字会和原子弹手术医院接受了Episil®治疗.
- 使用客观 (CTCAE v3.0) 和主观 (原始评估协议) 措施来评估口腔粘膜炎的严重程度.
主要成果:
- 84%的参与者认为Episil®的感觉非常好或好.
- 粘膜炎的严重程度在19%的患者下降,特别是在多个受影响部位的患者中.
- 据报道,疼痛缓解,言语和食功能显著改善,特别是在3级粘膜炎中.
结论:
- 在患有血液性恶性瘤的患者中,Episil®在治疗口腔粘膜炎方面表现出有效性.
- 对于影响多个口腔部位的粘膜炎患者来说,它特别有益.
- 这种材料可以改善疼痛,语言和食功能,提高患者的生活质量.
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