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下垂体:对一系列19名患者的描述性分析-多中心体验

Qiang Xue¹, Xiuhua Shi², Xiaoling Fu³

¹Departments of Neurosurgery, The Third Affiliated Hospital, Naval Medical University, Shanghai, 200438, China.

European journal of medical research

|May 2, 2024

概括

由于非特异性症状,诊断垂体 (PA) 是具有挑战性的,往往导致误诊. 有效的治疗依赖于手术干预和术后抗生素,以获得有利的预后.

科学领域:

神经外科神经外科
内分泌学在内分泌学.
病理学病理学病理学

背景情况:

垂体 (PA) 是一种罕见的细胞质 (0.3-0.5%),由于不特定的临床表现,经常被误诊为垂体腺瘤,瘤或拉特克囊.
术前诊断PA是困难的,通常需要通过手术活检进行体内病理学确认.

研究的目的:

调查与垂体 (PA) 相关的诊断挑战.
评估将手术内外科手术与术后抗生素治疗结合用于PA管理的有效性.

主要方法:

通过组织病理学对19名被诊断患有PA的患者的回顾性分析.
患者在经过全面的手术前评估 (例行测试,内分泌检测,成像) 后接受了跨形手术 (TSS).
对PA的不同治疗策略进行比较,以确定最佳预后.

主要成果:

头痛是最常见的症状,其次是下垂体相关的症状 (例如,疲劳,体重减轻,缺血症).
在19名患者中,没有一个在手术前被正确诊断为PA;许多细胞病变被误诊.
通过手术干预和活跃的术后抗生素治疗,获得了有利的预后.

结论:

术后发现和抗生素治疗对于诊断PA至关重要,鉴于诊断的不确定性.
最佳的手术干预与活跃的术后抗生素治疗相结合,有效地解决了管理垂体的挑战.

关键词:

诊断诊断诊断诊断诊断在 PA PA PA 里面.跨形外科手术是如何进行的治疗方法治疗方法

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