儿童脑瘤治疗后疲劳的发展在瘤位置之间没有差异
Elin Irestorm1,2, Antoinette Y N Schouten-van Meeteren2, Marloes van Gorp2
1Faculty of Medicine, Department of Paediatrics, Lund University, Lund, Sweden.
Pediatric blood & cancer
|May 2, 2024
概括
儿童大脑瘤幸存者经历了显著的疲劳,受治疗和社会人口因素的影响,而不是瘤的位置. 在治疗结束多年后,脆弱的患者可能需要有针对性的支持.
科学领域:
- 儿科瘤学 儿科瘤学
- 神经瘤学神经瘤学
- 癌症的生存率 癌症的生存率
背景情况:
- 与其他儿童癌症幸存者相比,患有脑瘤的儿童和青少年报告的疲劳水平更高.
- 瘤的位置是影响儿童脑瘤患者疲劳发展的潜在因素.
研究的目的:
- 为了研究儿童脑瘤幸存者的疲劳的纵向发展.
- 根据瘤位置确定疲劳的危险因素.
主要方法:
- 在425名儿科脑瘤患者中使用PedsQL多维疲劳量表对疲劳的长度评估.
- 分析了使用混合模型在治疗后8年内对1235次疲劳评估的分析.
- 根据瘤位置对疲劳发展和风险因素的分层:下门,上门半球和上门中线.
主要成果:
- 认知疲劳随着时间的推移而增加;睡眠休息和一般疲劳显示出两相模式.
- 在瘤位置之间没有观察到总体疲劳水平的显著差异.
- 放射治疗 (下),集中护理 (上中线) 和女性性别 (上半球) 与特定瘤群体的疲劳增加有关.
- 较高的家长教育与所有瘤部位的疲劳减少有关.
结论:
- 儿科脑瘤幸存者的疲劳发展主要与社会人口统计学和治疗变量有关,而不是瘤位置.
- 医疗保健提供者应监测治疗后多年的持续疲劳.
- 来自低/中等教育背景的患者可能需要有针对性的干预和支持.
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