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Updated: Jun 27, 2025

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斯特里克托萨米德通过激活PI3K/AKT通路促进伤口愈合

Gu-Xu Ming1, Jun-Yan Liu1, Yu-Huang Wu1

  • 1Hainan Provincial Key Laboratory R&D on Tropical Herbs, Haikou Key Laboratory of Li Nationality Medicine, School of Pharmacy, Hainan Medical University, Haikou, China.

Heliyon
|May 3, 2024
PubMed
概括

来自Nauclea officinalis的strictosamide (STR) 通过减少炎症和增强原蛋白,显著加速大鼠的伤口愈合. 这种化合物激活PI3K/AKT通路,为创伤治疗提供了新的潜力.

关键词:
分子对接是分子对接.网络药理学 网络药理学通过PI3K/AKT路径.斯里克托萨米德是一种严格的胺.在体内和体外验证.伤口愈合 伤口愈合

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