在一个月内使用倾向性得分匹配方法对肺结核老年患者再入院的风险因素进行研究
Yinping Feng1, Jing Guo1, Shuirong Luo1
1Department of Tuberculosis, Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Traditional Chinese Medicine, Lishui Tuberculosis Clinical Medical Research Center, Lishui, Zhejiang, People's Republic of China.
Infection and drug resistance
|May 3, 2024
概括
肺结核 (PTB) 的老年患者面临感染,药物诱导肝损伤 (DILI),急性心力衰竭 (AHF),慢性病 (CKD) 和肺外结核 (EPTB) 的再入院风险. 早期干预对于管理这些风险因素至关重要.
科学领域:
- 老年医学 老年医学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 患有肺结核 (PTB) 的老年患者有重新入院的高风险.
- 确定特定的风险因素对于有效的患者管理和减少医疗保健负担至关重要.
研究的目的:
- 探索与被诊断患有肺结核 (PTB) 的老年患者一个月再入院相关的风险因素.
- 使用倾向分数匹配 (PSM) 来控制分析中的混变量.
主要方法:
- 从2020年1月至2023年10月期间入院的老年PTB患者的临床数据的回顾性分析.
- 患者在出院后一个月内被分为非再入院和再入院组.
- 使用倾向分数匹配 (PSM) 来平衡基线特征,然后进行多变量逻辑回归.
主要成果:
- 总共有1268名老年PTB患者被分析;288对使用PSM进行匹配.
- 在匹配后,在群体之间的人口统计或基线病史中没有观察到显著差异.
- 感染,药物诱导性肝损伤 (DILI),急性心力衰竭 (AHF),慢性病 (CKD) 和肺外结核 (EPTB) 被确定为重新入院的重要危险因素.
结论:
- 感染,DILI,AHF,CKD和EPTB是老年PTB患者一个月再入院的关键风险因素,即使在控制混因子后.
- 这些发现强调了针对这一弱势群体进行有针对性的早期干预和主动管理战略的必要性.
相关概念视频
01:28Pulmonary Tuberculosis V
178
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
178
01:29Pulmonary Tuberculosis I
241
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
241
01:31Pulmonary Tuberculosis III
324
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
324
01:28Pulmonary Tuberculosis II
226
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
226
01:26Pulmonary Tuberculosis IV
140
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
140
01:30Pneumonia I: Introduction
226
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
226