在制造过程中GD2TRAC-CAR T细胞的代谢原始化促进了记忆表型,同时增强了持久性

Dan Cappabianca1,2, Dan Pham2,3, Matthew H Forsberg4

  • 1Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA.

概括

在CAR T细胞制造过程中的代谢原始化优化了细胞表型. 这一过程丰富了记忆T细胞并提高了持久性,在体内潜在地增强了抗瘤反应.

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