中国内脏脂肪指数和心血管疾病之间的剂量反应关系:一项全国前性队列研究
Yongcheng Ren1,2, Qing Hu2, Zheng Li2
1Henan Provincial Key Laboratory of Digital Medicine, Affiliated Central Hospital of Huanghuai University, Zhumadian, He'nan, China.
Frontiers in endocrinology
|May 3, 2024
概括
中国内脏肥胖指数 (CVAI) 是内脏肥胖的可靠指标,有效预测心血管疾病 (CVD) 风险. 这项研究证实了CVAI在识别患心血管疾病事件风险较高的个体方面的卓越能力.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 肥胖问题研究研究
背景情况:
- 中国内脏肥胖指数 (CVAI) 是对内脏肥胖的公认衡量标准.
- 然而,它与心血管疾病 (CVD) 风险的关联需要进一步调查.
研究的目的:
- 探索CVAI与发生的心血管疾病,心脏病和中风之间的联系.
- 将CVAI的预测能力与其他已确定的肥胖指数进行比较.
主要方法:
- 一项针对7439名45岁以上的中国成年人的全国性队列研究 (CHARLS).
- 考克斯回归和受限立方线用于关联和剂量反应分析.
- 接收机操作员特征 (ROC) 分析,以比较CVAI,VAI,ABSI,CI,WC和BMI的预测能力.
主要成果:
- 在7年间,发现了1326例心血管疾病,1032例心脏病和399例中风病例.
- 较高的CVAI四分位数显示心血管疾病,心脏病和中风的风险显著增加.
- 与其他指数相比,CVAI表现出与这些条件的线性关联以及优越的预测价值.
结论:
- CVAI与心血管疾病,心脏病和中风的风险增加有线相关.
- 在评估的指数中,CVAI在预测事件CVD方面表现最好.
- CVAI是一个可靠和适用的指数,用于识别心血管疾病风险较高的个人.
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