75岁以上无症状参与者的监视结肠镜检查结果
Madelyn Agaciak1, Molla M Wassie2, Kalindra Simpson3
1Department of Medicine, College of Medicine and Public Health Flinders University Bedford Park South Australia Australia.
在75岁及以上的个体中,对结肠直肠癌 (CRC) 的监测结肠镜检查发现超过三分之一的病例是晚期腺瘤. 以前的CRC,年龄较大和吸烟预测CRC,这表明持续监测可能有利于选择患者.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- 目前的指导方针一般不建议在75岁以上对结肠直肠癌 (CRC) 进行监视结肠镜检查.
- 然而,老年人继续接受监测,需要了解相关风险和益处.
研究的目的:
- 为了确定75岁及以上接受监视结肠镜检查的75岁及以上个体中晚期腺瘤和CRC的发病率.
- 在这个人口群体中确定晚期腺瘤和CRC的预测因子.
主要方法:
- 在南澳大利亚CRC监测计划 (2015-2020) 中,对75岁及以上无症状个体进行了回顾性队列研究.
- 提取的数据包括人口统计数据,个人/家庭CRC病史,并发症,多药学和结肠镜检查结果.
- 多变量波桑回归分析评估了临床变量与结果之间的关联.
主要成果:
- 分析了来自574名参与者 (75-91岁) 的698个监测结肠镜.
- CRC发生率为1.6%,在37.9%的手术中检测到晚期腺瘤.
- 预测CRC的因素包括以前的CRC,年龄≥85,和活跃的吸烟. 在先前的结肠镜检查和多药学预测在监测时的先进腺瘤.
结论:
- 高度瘤在接受监视结肠镜检查的老年人中很常见.
- 在75岁以后继续监测可能是有必要的,对于有CRC病史或是活跃吸烟者的个人.
- 持续监测的决定应考虑个体患者的因素,偏好和健康状况.
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